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Nepal is open for the autumn season, and glad you are coming.

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Travel Himalaya Nepal
Prescription only in most countries
Not ours to sell

The one thing on this page you cannot buy from a link

Acetazolamide (Diamox) — a conversation with your doctor

Prescription only in most countries

Acetazolamide is genuinely effective for acclimatisation and it is also a prescription drug with real side effects and real contraindications — sulfa allergy among them. Have that conversation at home, not in a Thamel pharmacy.

Prescription medication. Ask your own doctor — we are guides, not clinicians.

What you get

  • Well-evidenced for speeding acclimatisation
  • Widely prescribed for Himalayan trekking
  • Your doctor knows your history; a shop assistant does not

What it costs you

  • Tingling extremities and increased urination are normal and unpleasant
  • Contraindicated with sulfa allergy
  • It assists acclimatisation — it does not license going higher, faster

Do not buy this if: Anyone hoping to skip acclimatisation days. No drug replaces walking high and sleeping low.

The alternatives

Everything else we recommend in altitude & medication, including the ones we think suit a different trekker.

Fingertip pulse oximeter — A trend to watch, not a number to trustUseful with caveats

A trend to watch, not a number to trust

Fingertip pulse oximeter

Useful for spotting a trend across several mornings, and actively dangerous if you treat a single reading as a verdict — cold fingers alone can drop a reading by several points, and consumer devices are not calibrated for 5,000 m.

Skip it ifAnyone who would use it to overrule how they feel or what a guide says. Symptoms decide; the number does not.