Best overallThe boot for a full circuit with a real pack on your back
Salomon Quest 4 GTX
Stiff enough to carry weight over a pass and still comfortable on day fourteen — you pay for that in weight and in a break-in period you cannot skip.

Merrell Moab 3 Mid Waterproof
Mid-height, waterproof membrane, minimal break-in
4.4 on Amazon (241 ratings)
Covers every lodge trek below 5,000 m for a fraction of the money — the sole is softer and the upper wears out faster, which is fine if this is a one-trip boot.
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Do not buy this if: You are carrying your own load over a 5,000 m pass, or you expect this to be your boot for years. Buy once, properly, instead.
Not every route needs it. These are the ones where our guides would put it on your list.
Everything else we recommend in trekking boots, including the ones we think suit a different trekker.
Best overallSalomon Quest 4 GTX
Stiff enough to carry weight over a pass and still comfortable on day fourteen — you pay for that in weight and in a break-in period you cannot skip.
Kindest out of the boxLowa Renegade GTX Mid
The most forgiving first week of any boot we see on the trail; the trade is a softer sole that flexes more than it should under a heavy load.