Kindest out of the boxThe one to buy if you are short on break-in time
Lowa Renegade GTX Mid
The most forgiving first week of any boot we see on the trail; the trade is a softer sole that flexes more than it should under a heavy load.

Salomon Quest 4 GTX
Mid-weight, above-ankle, Gore-Tex, ~1.3 kg/pair
4.6 on Amazon (2,061 ratings)
Stiff enough to carry weight over a pass and still comfortable on day fourteen — you pay for that in weight and in a break-in period you cannot skip.
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Do not buy this if: You are doing Poon Hill or a short lodge trek under 3,500 m with a porter carrying the load. This is more boot than that walk needs.
Not every route needs it. These are the ones where our guides would put it on your list.
Everything else we recommend in trekking boots, including the ones we think suit a different trekker.
Kindest out of the boxLowa Renegade GTX Mid
The most forgiving first week of any boot we see on the trail; the trade is a softer sole that flexes more than it should under a heavy load.
Best valueMerrell Moab 3 Mid Waterproof
Covers every lodge trek below 5,000 m for a fraction of the money — the sole is softer and the upper wears out faster, which is fine if this is a one-trip boot.